They could do a movie like this:
Mac's dead, Heather runs a very small, underground Department H; "agents" have left for the U.S. and reformed SHIELD is trying to get rid of groups like Dept. H. Judd beats up jerks in a bar, gets hired by Heather to run security 'despite his past and the law'. He accepts, meets Nemesis (who sits there, no talk, sleep, or eat), Killjov (also no talk, but he works out, blades are formed by nannies, Judd knows who he really is [Outcast member] but says nothing), Shaman (wants to keep Talisman away from H), and Walter (who Judd thinks is dead, and is glad Heather has a scientist the equal of Reed Richards on staff, somehow). Nemesis calls him Puck when they finally meet.
Joshua Lord is filthy rich and a Utilitarian Utopian, wants to rid the world of suffering but really wants to create uber-humans like himself. He creates cyborgs and super soldiers for sale, keeps the unique ones for his own para-military. He has the power to wipe out hundreds of millions and remake the survivors into uber-humans.
Heather has the Vindicator suit Mac made but refuses to look at it. Lord, who refers to himself as Master, learns of Department H's continued existence and believes they need to be gotten rid of as they have access to intel that would expose him, even though they don't know it. Unfortunately for him they do discover it and let the news out. Lord denies it, calls it a conspiracy to sully his name all but sends his paramilitary to destroy H when Heather et al are called out by the government to answer for the leak and it's veracity. Lord's squad succeed in destroying H, since it's pretty much abandoned except for some soldiers (who they kill). The government is suspicious and lets Heather have another facility to run H from. Puck is incensed by the failure of people to realize what Lord is doing, and takes over to form Alpha Flight, now that he knows Walter is Sasquatch. Over Shaman's head he recruits Talisman. Nemesis finally does something and it's to agree with him, time to take out Lord. They go without Heather's blessing (she thinks it's all revenge, after all they have no corroboration of the intel on Lord at all). They sneak in and find children (Children of the Night, the sign says) who Lord is experimenting on to find the secret of perfect uber-humans. Against Heather's remote objections they lead the children to safety. Lord's squad is sent to kill AF and the children. Though they are outnumbered and alone Puck and his team hold out, but some children die. Master shows up in his advanced mech suit to end the battle but Heather shows up as Vindicator and kills him. Lord's team is defeated as Shaman and Talisman take away their abilities (they can come back in movie two as the Hardcases or whatever).
Back at H the five children start to die but Walter saves them. Heather keeps Dept. H with a slightly larger science/engineering staff (two more people) and AF gets to stay in the shadows. The children wake up and one finds she can move through objects, another can turn his body appendages into metal parts, another can hide in plain sight, another looks like an alien fish girl….